Health practitioners rely on case management programs to address patients’ social care needs

Health professionals recognize that social factors such as food, housing and economic insecurity, affect health outcomes. Researchers conducted a qualitative study to gain practical insights into strategies used by clinicians, leaders and policymakers to address patients’ social needs in the United States. They selected sites to ensure diversity in ownership, structure, geography and urbanicity, ranging […]

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Radiotherapy may explain why childhood cancer survivors often develop metabolic disease

Decades after battling childhood cancer, survivors often face a new challenge: cardiometabolic disease. A spectrum of conditions that includes coronary heart disease and diabetes, cardiometabolic disease typically impacts people who are obese, elderly, or insulin resistant. For reasons yet unknown, young, seemingly healthy adults who survived childhood cancer are also at risk. Radiation therapy may […]

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A target for potential cancer drugs may, in fact, worsen disease

In recent years, much scientific effort and funding has focused on developing drugs that target an enzyme with the unwieldy name of Src homology 2-containing protein tyrosine phosphatase 2 or more briefly, Shp2. Shp2 is a phosphotyrosine phosphatase; its job is to remove phosphates from protein tyrosine residues, aiding and abetting signal communications within cells. […]

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Research identifies new imaging biomarkers that predict antidepressant response

The outcome predictive models were developed in part using data from a large multi-center National Institute of Mental Health-funded study and published in the journal Biological Psychiatry. The findings provide strong evidence that the current trial-and-error approach used in clinical practice for the selection of the right antidepressant can be replaced with this new precision […]

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Person-centered primary care measure shows validity across 35 countries

Researchers administered the Person-Centered Primary Care Measure (PCPCM) in 28 languages to 35 Organisation for Economic Cooperation and Development countries to examine the reliability and validity of the measure and to explore the differences in primary care across 35 OECD countries. The PCPCM is an 11-item, patient-reported measure developed in 2017 to assess primary care […]

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